Chao‐Yie Yang

The PDBbind Database:  Methodologies and Updates

Renxiao Wang, Xueliang Fang, Yipin Lu et al. · Journal of Medicinal Chemistry · 2005 · 913 citations

Engineering, Pdbbind Database, Big Data Indexing +19

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

Longchuan Bai, Haibin Zhou, Renqi Xu et al. · Cancer Cell · 2019 · 575 citations · Full text

Cancer Research, Medicine, Small Molecules +9

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

Xin Han, Chao Wang, Chong Qin et al. · Journal of Medicinal Chemistry · 2019 · 371 citations · Full text

Androgen Receptor, Urology, Drug Targeting +11

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Bing Zhou, Jiantao Hu, Fuming Xu et al. · Journal of Medicinal Chemistry · 2017 · 351 citations · Full text

Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins

Guoping Wang, Zaneta Nikolovska‐Coleska, Chao‐Yie Yang et al. · Journal of Medicinal Chemistry · 2006 · 293 citations · Full text