Jiuling Yang

Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression

Yangbing Li, Jiuling Yang, Angelo Aguilar et al. · Journal of Medicinal Chemistry · 2018 · 291 citations · Full text

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Chong Qin, Yang Hu, Bing Zhou et al. · Journal of Medicinal Chemistry · 2018 · 258 citations · Full text

Molecular Biology, Bet Proteins, Bet Inhibitors +22

Simple Structural Modifications Converting a Bona fide MDM2 PROTAC Degrader into a Molecular Glue Molecule: A Cautionary Tale in the Design of PROTAC Degraders

Jiuling Yang, Yangbing Li, Angelo Aguilar et al. · Journal of Medicinal Chemistry · 2019 · 169 citations · Full text

Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)–Mixed Lineage Leukemia (MLL) Protein–Protein Interaction

Hacer Karataş, Yangbing Li, Liu Liu et al. · Journal of Medicinal Chemistry · 2017 · 94 citations

Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells

Lisa L. Kirkemo, Susanna K. Elledge, Jiuling Yang et al. · eLife · 2022 · 47 citations · Full text

Biomolecular Tool, Cell Adhesion, Glycobiology +20