Concepedia

Hacer Karataş

HK

20

Publications

1.4K

Citations

16

H-Index

2004

Active since

Affiliations

University of Michigan(Current)

Max Planck Institute of Molecular Physiology

TU Dortmund University

AstraZeneca (Sweden)

Lead Discovery Center (Germany)

Hacer Karataş is an author at University of Michigan specializing in medicine, molecular biology, and drug discovery.

Top concepts

MedicineBiochemistryCell BiologyPharmacologyDrug DiscoveryChemical BiologyNatural SciencesMolecular BiologyMolecular DockingSmall Molecules

Publications per year

2004–2023

20

Publications

20

Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia

Fang Cao, Elizabeth C. Townsend, Hacer Karataş et al. · Molecular Cell · 2014 · 296 citations · Full text

Hematological Malignancy, Chromatin, Mixed-phenotype Acute Leukemia +6

High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction

Hacer Karataş, Elizabeth C. Townsend, Fang Cao et al. · Journal of the American Chemical Society · 2012 · 210 citations · Full text

Mll1/wdr5 Protein–protein Interaction, Drug Target, Mixed Lineage +18

Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)–Mixed Lineage Leukemia (MLL) Protein–Protein Interaction

Hacer Karataş, Yangbing Li, Liu Liu et al. · Journal of Medicinal Chemistry · 2017 · 94 citations

Structure-Based Design of High-Affinity Macrocyclic Peptidomimetics to Block the Menin-Mixed Lineage Leukemia 1 (MLL1) Protein–Protein Interaction

Haibin Zhou, Liu Liu, Jing Huang et al. · Journal of Medicinal Chemistry · 2012 · 89 citations · Full text

The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis

Luca Laraia, Alexandra Friese, Dale Corkery et al. · Nature Chemical Biology · 2019 · 89 citations · Full text

Cell Autophagy, Autophagy, Lipophagy +5

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