Elizabeth C. Townsend

Molecular basis of USP7 inhibition by selective small-molecule inhibitors

A.P. Turnbull, Stephanos Ioannidis, Wojciech Krajewski et al. · Nature · 2017 · 448 citations

Drug Target, Usp7 Inhibition, Medicine +4

High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction

Hacer Karataş, Elizabeth C. Townsend, Fang Cao et al. · Journal of the American Chemical Society · 2012 · 210 citations · Full text

Mll1/wdr5 Protein–protein Interaction, Drug Target, Mixed Lineage +18

Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)–Mixed Lineage Leukemia (MLL) Protein–Protein Interaction

Hacer Karataş, Yangbing Li, Liu Liu et al. · Journal of Medicinal Chemistry · 2017 · 94 citations

Analysis of the Binding of Mixed Lineage Leukemia 1 (MLL1) and Histone 3 Peptides to WD Repeat Domain 5 (WDR5) for the Design of Inhibitors of the MLL1−WDR5 Interaction

Hacer Karataş, Elizabeth C. Townsend, Denzil Bernard et al. · Journal of Medicinal Chemistry · 2010 · 70 citations · Full text

Mll1 Activity, Protein Assembly, Mll1−wdr5 Interaction +17

Decreasing Phosphatidylcholine on the Surface of the Lipid Droplet Correlates with Altered Protein Binding and Steatosis

Laura Listenberger, Elizabeth C. Townsend, Cassandra Rickertsen et al. · Cells · 2018 · 60 citations · Full text

Proteinlipid Interaction, Lipid Movement, Rat Model +17