Jiantao Hu

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression

Bing Zhou, Jiantao Hu, Fuming Xu et al. · Journal of Medicinal Chemistry · 2017 · 361 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

Discovery of ERD-308 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Estrogen Receptor (ER)

Jiantao Hu, Biao Hu, Mingliang Wang et al. · Journal of Medicinal Chemistry · 2019 · 271 citations

Life Sciences, Medicinal Chemistry, Oncology +13

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Chong Qin, Yang Hu, Bing Zhou et al. · Journal of Medicinal Chemistry · 2018 · 263 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer

Longchuan Bai, Bing Zhou, Chao‐Yie Yang et al. · Cancer Research · 2017 · 199 citations · Full text

Life Sciences, Oncology, Pharmacology +17

A general and efficient approach to 2H-indazoles and 1H-pyrazoles through copper-catalyzed intramolecular N–N bond formation under mild conditions

Jiantao Hu, Yong‐Feng Cheng, Yiqing Yang et al. · Chemical Communications · 2011 · 124 citations

Pharmacy, Chemistry, Medicinal Chemistry +9