Renqi Xu

A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

Longchuan Bai, Haibin Zhou, Renqi Xu et al. · Cancer Cell · 2019 · 618 citations · Full text

Medicine, Molecular Biology, Oncology +7

Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein

Haibin Zhou, Longchuan Bai, Renqi Xu et al. · Journal of Medicinal Chemistry · 2019 · 213 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +12

A selective small-molecule STAT5 PROTAC degrader capable of achieving tumor regression in vivo

Atsunori Kaneshige, Longchuan Bai, Mi Wang et al. · Nature Chemical Biology · 2023 · 63 citations

Pharmacy, Medicinal Chemistry, Oncology +7

SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression

Haibin Zhou, Longchuan Bai, Renqi Xu et al. · ACS Medicinal Chemistry Letters · 2021 · 48 citations · Full text

Medicine, Molecular Biology, Oncology +8

Discovery of a Potent and Selective STAT5 PROTAC Degrader with Strong Antitumor Activity <i>In Vivo</i> in Acute Myeloid Leukemia

Atsunori Kaneshige, Longchuan Bai, Mi Wang et al. · Journal of Medicinal Chemistry · 2023 · 31 citations

Pharmacy, Medicinal Chemistry, Oncology +13