Ke Ding

Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of Medicinal Chemistry · 2006 · 692 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Sanjeev Shangary, Dongguang Qin, Donna McEachern et al. · Proceedings of the National Academy of Sciences · 2008 · 656 citations · Full text

Medicine, Oncology, Pharmacology +13

Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors

Ke Ding, Yipin Lu, Zaneta Nikolovska‐Coleska et al. · Journal of the American Chemical Society · 2005 · 649 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species

Yanli Jin, Zhongzheng Lu, Ke Ding et al. · Cancer Research · 2010 · 333 citations · Full text

Medicine, Oncology, Pharmacology +14

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

James D. Vasta, Cesear Corona, Jennifer Wilkinson et al. · Cell chemical biology · 2017 · 293 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14