James D. Vasta

Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action

Kristin M. Riching, Sarah D. Mahan, Cesear Corona et al. · ACS Chemical Biology · 2018 · 305 citations · Full text

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

James D. Vasta, Cesear Corona, Jennifer Wilkinson et al. · Cell chemical biology · 2017 · 281 citations · Full text

Drug Target, Wide-spectrum Kinase Profiling, Kinase Inhibitors +20

Discovery of a selective inhibitor of doublecortin like kinase 1

Fleur M. Ferguson, Behnam Nabet, Srivatsan Raghavan et al. · Nature Chemical Biology · 2020 · 111 citations · Full text

Medicine, Receptor Tyrosine Kinase, Kinase 1 +5

Quantifying CDK inhibitor selectivity in live cells

Carrow I. Wells, James D. Vasta, Cesear Corona et al. · Nature Communications · 2020 · 109 citations · Full text

KRAS is vulnerable to reversible switch-II pocket engagement in cells

James D. Vasta, D. Matthew Peacock, Qinheng Zheng et al. · Nature Chemical Biology · 2022 · 97 citations · Full text