Fleur M. Ferguson

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development

Katherine A. Donovan, Fleur M. Ferguson, Jonathan W. Bushman et al. · Cell · 2020 · 346 citations · Full text

Geometric Modeling, Robotics, Engineering +11

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong et al. · Nature Communications · 2020 · 293 citations · Full text

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

M. Catarina Silva, Fleur M. Ferguson, Quan-Ying Cai et al. · eLife · 2019 · 256 citations · Full text

A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

Matthias G. J. Baud, Enrique Lin-Shiao, Teresa A.F. Cardote et al. · Science · 2014 · 146 citations

Engineering, Molecular Biology, Controlled Selectivity +23

Selective Mediator dependence of cell-type-specifying transcription

Martin G. Jaeger, Björn Schwalb, Sebastian D. Mackowiak et al. · Nature Genetics · 2020 · 137 citations · Full text

Transcriptional Regulation, Gene Regulation, Gene Regulatory Network +6