A compendium of RNA-binding motifs for decoding gene regulation

Debashish Ray, Hilal Kazan, Kate B. Cook, +32

Nature

Sequence MotifNatural SciencesRna Binding ProteinsRna BiologyMolecular Biology +5

The dTAG system for immediate and target-specific protein degradation

Behnam Nabet, Justin M. Roberts, Dennis L. Buckley, +15

Nature Chemical Biology

Protein FunctionProtein ExpressionProtein FoldingNatural SciencesMolecular Biology +4

YY1 Is a Structural Regulator of Enhancer-Promoter Loops

Abraham S. Weintraub, Charles H. Li, Alicia V. Zamudio, +13

Cell

Transcriptional RegulationGeneticsGene RegulationEnhancer-promoter LoopsMolecular Genetics +5

ESRP1 and ESRP2 Are Epithelial Cell-Type-Specific Regulators of FGFR2 Splicing

Claude C. Warzecha, Trey K. Sato, Behnam Nabet, +2

Molecular Cell

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationSystems Biology +4

Transcription control by the ENL YEATS domain in acute leukaemia

Michael A. Erb, Thomas G. Scott, Bin E. Li, +17

Nature

Hematological MalignancyChromatinTranscriptional RegulationSystems BiologyTranscription Control +6

Mutant NPM1 Maintains the Leukemic State through HOX Expression

Lorenzo Brunetti, Michael C. Gundry, Daniele Sorcini, +14

Cancer Cell

Genome InstabilityMutant Npm1Molecular BiologyMedicineCell Biology

Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules

Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, +10

Nature Communications

Exploring Targeted Degradation Strategy for Oncogenic KRASG12C

Mei Zeng, Yuan Xiong, Nozhat Safaee, +16

Cell chemical biology

Oncogenic AgentMolecular BiologyDegradation ReactionDegradation StrategyProtein Degradation +1

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma

Rhamy Zeid, Matthew A. Lawlor, Evon Poon, +16

Nature Genetics

Cell RegulationMycn-dependent Transcriptional AmplificationMedicineCell BiologyTumor Biology

MELK is not necessary for the proliferation of basal-like breast cancer cells

Hai‐Tsang Huang, Hyuk‐Soo Seo, Tinghu Zhang, +16

eLife

Breast OncologyCancer BiologyTumor BiologySelectivity IssuesDrug Discovery Efforts +14