Kip A. West

Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells.

Amy S. Clark, Kip A. West, Samantha A. Streicher et al. · PubMed · 2002 · 591 citations

Breast Oncology, Chemoprevention Strategy, Apoptosis +22

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

Vincent M. Isabella, Binh Ha, Mary Joan Castillo et al. · Nature Biotechnology · 2018 · 548 citations

Biosynthesis, Engineering, Biotechnology +6

Metabolic modulation of tumours with engineered bacteria for immunotherapy

Fernando P. Canale, Camilla Basso, Gaia Antonini et al. · Nature · 2021 · 541 citations

Cancer Immunosurveillance, Engineered Bacteria, Medicine +6

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 533 citations

Vitro Potency, Signal Transduction, Medicine +10

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

Kip A. West, John Brognard, Amy S. Clark et al. · Journal of Clinical Investigation · 2003 · 511 citations · Full text

Asthma, Apoptosis, Cell Death +19