Fernando P. Canale

Metabolic modulation of tumours with engineered bacteria for immunotherapy

Fernando P. Canale, Camilla Basso, Gaia Antonini et al. · Nature · 2021 · 541 citations

Cancer Immunosurveillance, Engineered Bacteria, Medicine +6

CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells

Fernando P. Canale, María C. Ramello, Nicolás Gonzalo Núñez et al. · Cancer Research · 2017 · 402 citations · Full text

Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

Kevin M. Tharp, Kelly Kersten, Ori Maller et al. · Nature Cancer · 2024 · 187 citations · Full text

Tumor-associated Macrophages, Cancer Immunosurveillance, Breast Cancer Microenvironment +11

Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L

María C. Ramello, Jimena Tosello, Fernando P. Canale et al. · Cell Death and Disease · 2014 · 49 citations · Full text

Polyfunctional KLRG-1+CD57+ Senescent CD4+ T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients

María C. Ramello, Nicolás Gonzalo Núñez, Jimena Tosello et al. · Frontiers in Immunology · 2021 · 42 citations · Full text