Concepedia

Author

John Brognard

Cancer Research UK Manchester InstituteORCID

Also Known As

Anna Marusiak, Brognard, John, J Brognard, J. Brognard, John Brognard, M. Rezaee, Matthew G Krebs, Moahmmad Rezaee, Steven D. Cappell

178

Publications

6K

Citations

31

H-Index

53

Concepts

All Affiliations

Cancer Research UK Manchester InstituteNational Cancer InstituteUniversity of ManchesterCenter for Cancer ResearchUniversity of California San Diego
JB

About

John Brognard is an author at Cancer Research UK Manchester Institute specializing in cell biology, medicine, and cell signaling.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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3.2K

2

Natural Sciences

4

4

1.1K

3

Engineering

1

1

41

4

Health Sciences

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Allergy

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511

John Brognard

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33

Publications

5.3K

Citations

28

H-Index

YearCitations

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

John Brognard, Amy S. Clark, Yucheng Ni,

PubMed

2001

892

PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms

John Brognard, Emma Sierecki, Tianyan Gao,

Molecular Cell

2007

573

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

Kip A. West, John Brognard, Amy S. Clark,

Journal of Clinical Investigation

2003

511

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

Kip A. West, John Brognard, Amy S. Clark,

Journal of Clinical Investigation

2003

498

Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

Corina E. Antal, Andrew Hudson, Emily L. Kang,

Cell

2015

330

Tobacco components stimulate Akt-dependent proliferation and NFκB-dependent survival in lung cancer cells

Junji Tsurutani, S. Sianna Castillo, John Brognard,

Carcinogenesis

2005

287

The mRNA Surveillance Protein hSMG-1 Functions in Genotoxic Stress Response Pathways in Mammalian Cells

Kathryn M. Brumbaugh, Diane M. Otterness, Christoph Geisen,

Molecular Cell

2004

214

The Phosphatase PHLPP Controls the Cellular Levels of Protein Kinase C

Tianyan Gao, John Brognard, Alexandra C. Newton

Journal of Biological Chemistry

2007

207

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

María Romina Girotti, Filipa M. Lopes, Natasha Preece,

Cancer Cell

2014

201

Novel PI Analogues Selectively Block Activation of the Pro-survival Serine/Threonine Kinase Akt

Alan P. Kozikowski, Haiying Sun, John Brognard,

Journal of the American Chemical Society

2003

196

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