Concepedia

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

Vincent M. Isabella, Binh Ha, Mary Joan Castillo, David Lubkowicz, Sarah E. Rowe, Yves Millet, Cami Anderson, Ning Li, Adam Fisher, Kip A. West,

Nature Biotechnology · 2018 · 579 citations · 39 references

DOI

Concepts

References

39

Phenylalanine hydroxylase deficiency: diagnosis and management guideline

Jerry Vockley, Hans C. Andersson, Kevin M. Antshel et al. · Genetics in Medicine · 2014 · 722 citations · Full text

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Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

In Young Hwang, Elvin Koh, Adison Wong et al. · Nature Communications · 2017 · 465 citations · Full text

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Biocontainment of genetically modified organisms by synthetic protein design

Daniel J. Mandell, Marc J. Lajoie, Michael T. Mee et al. · Nature · 2015 · 462 citations · Full text

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Programmable probiotics for detection of cancer in urine

Tal Danino, Arthur Prindle, Gabriel A. Kwong et al. · Science Translational Medicine · 2015 · 462 citations · Full text

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Synthetic Biology Moving into the Clinic

Warren C. Ruder, Ting Lu, James J. Collins · Science · 2011 · 426 citations

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