Concepedia

Mary Joan Castillo

MJ

6

Publications

884

Citations

6

H-Index

2015

Active since

Affiliations

Synlogic (United States)(Current)

Mary Joan Castillo is an author at Synlogic (United States) specializing in biomolecular engineering, engineering, and synthetic biology.

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Publications per year

2015–2021

6

Publications

6

Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria

Vincent M. Isabella, Binh Ha, Mary Joan Castillo et al. · Nature Biotechnology · 2018 · 548 citations

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Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study

Marja Puurunen, Jerry Vockley, Shawn Searle et al. · Nature Metabolism · 2021 · 146 citations

, , +8

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering

Kristin J. Adolfsen, Isolde Callihan, Catherine Monahan et al. · Nature Communications · 2021 · 91 citations · Full text

Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chip

Mark Nelson, Mark R. Charbonneau, Heidi G. Coia et al. · Nature Communications · 2021 · 70 citations · Full text

Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria

Mark R. Charbonneau, William S. Denney, Nicholas G. Horvath et al. · Communications Biology · 2021 · 19 citations · Full text

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