Shawn Searle

Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study

Marja Puurunen, Jerry Vockley, Shawn Searle et al. · Nature Metabolism · 2021 · 160 citations

Engineering, Biological Engineering, Biotechnology +5

Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial

Jerry Vockley, Neal Sondheimer, Marja Puurunen et al. · Nature Metabolism · 2023 · 73 citations

Pharmacy, Pharmacology, Pharmacotherapy +6

Randomized Crossover Trial to Compare Abuse Liability of Intravenous Remimazolam Versus Intravenous Midazolam and Placebo in Recreational Central Nervous System Depressant Users

Frank Schippers, Marija Pesic, Rob Saunders et al. · The Journal of Clinical Pharmacology · 2020 · 56 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +9

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects

Jason M. Gow, Wayne Tsuji, Gary J. Williams et al. · Arthritis Research & Therapy · 2015 · 27 citations · Full text

Medicine, Clinical Sciences, Pharmacokinetics +4

Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain

Shawn Searle, Derek Muse, Ed Paluch et al. · Clinical Journal of Pain · 2020 · 17 citations

Medicine, Oral Surgery, Orofacial Pain +16