Shawn Searle

Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study

Marja Puurunen, Jerry Vockley, Shawn Searle et al. · Nature Metabolism · 2021 · 146 citations

Engineering, Medicine, First-in-human Phase 1/2A +8

Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial

Jerry Vockley, Neal Sondheimer, Marja Puurunen et al. · Nature Metabolism · 2023 · 56 citations

Urology, Medicine, Pharmacology +4

Randomized Crossover Trial to Compare Abuse Liability of Intravenous Remimazolam Versus Intravenous Midazolam and Placebo in Recreational Central Nervous System Depressant Users

Frank Schippers, Marija Pesic, Rob Saunders et al. · The Journal of Clinical Pharmacology · 2020 · 54 citations · Full text

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteoarthritis subjects

Jason M. Gow, Wayne Tsuji, Gary J. Williams et al. · Arthritis Research & Therapy · 2015 · 26 citations · Full text

Rheumatology, Sclerostin, Musculoskeletal Research +11

Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain

Shawn Searle, Derek Muse, Ed Paluch et al. · Clinical Journal of Pain · 2020 · 17 citations