Concepedia

Kristy G. Kuplast

KG

4

Publications

912

Citations

4

H-Index

2006

Active since

Affiliations

Epizyme (United States)(Current)

Kristy G. Kuplast is an author at Epizyme (United States) specializing in medicine, pharmacology, and drug discovery.

Top concepts

MedicinePharmacologyDrug DiscoveryNeurologyEngineeringBiochemistryCell BiologyIon ChannelsNeuroscienceCell Signaling

Publications per year

2006–2015

4

Publications

4

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 533 citations

Vitro Potency, Signal Transduction, Medicine +10

T-Type Calcium Channel Blockers That Attenuate Thalamic Burst Firing and Suppress Absence Seizures

Elizabeth Tringham, Kim L. Powell, Stuart M. Cain et al. · Science Translational Medicine · 2012 · 207 citations

Synaptic Transmission, Neuromodulation Therapies, Neurotransmission +24

Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666

Kenneth W. Duncan, Nathalie Rioux, P. Ann Boriack‐Sjodin et al. · ACS Medicinal Chemistry Letters · 2015 · 149 citations · Full text

Materials Science, Medicinal Chemistry, Drug Target +14

Calsenilin interacts with transcriptional co‐repressor C‐terminal binding protein(s)

Nikhat F. Zaidi, Kristy G. Kuplast, Kevin J. Washicosky et al. · Journal of Neurochemistry · 2006 · 23 citations · Full text

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