Jing Yuan

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

Life Sciences, Cell Biology, Oncology +16

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 554 citations

Medicine, Oncology, Pharmacology +16

Hrp pilus: An <i>hrp</i> -dependent bacterial surface appendage produced by <i>Pseudomonas syringae</i> pv. <i>tomato</i>  DC3000

Elina Roine, Wensheng Wei, Jing Yuan et al. · Proceedings of the National Academy of Sciences · 1997 · 356 citations · Full text

Agriculture, Microbiology, Plant Pathology +17

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

Shifeng Pan, Xu Wu, Jiqing Jiang et al. · ACS Medicinal Chemistry Letters · 2010 · 328 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

A crucial requirement for Hedgehog signaling in small cell lung cancer

Luciano G. Martelotto, Martin Peifer, Martin L. Sos et al. · Nature Medicine · 2011 · 249 citations

Medicine, Cancer Biology, Oncology +14