Concepedia

Ying-Nan P. Chen

YP

Statistics

Publications

8

Citations

2.3K

H-Index

8

Active since

1991

Affiliations

Harvard University(Current)

Dana-Farber Cancer Institute

Ying-Nan P. Chen is an author at Harvard University specializing in life sciences, molecular oncology, and signal transduction.

Publications per year

1991–2020

8

Publications

8

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

, , +16

Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

Maı̈na Lepourcelet, Ying-Nan P. Chen, Dennis S. France et al. · Cancer Cell · 2004 · 647 citations · Full text

, , +14

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Ying-Nan P. Chen, Sushil Sharma, Timothy M. Ramsey et al. · Proceedings of the National Academy of Sciences · 1999 · 319 citations

, , +17

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen et al. · Journal of Medicinal Chemistry · 2016 · 291 citations · Full text

, , +17

Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein Degradation

Jing Zhang, Liqiang Fu, Bin Shen et al. · Cell chemical biology · 2020 · 53 citations · Full text

, , +11

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