Dennis S. France

Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex

Maı̈na Lepourcelet, Ying-Nan P. Chen, Dennis S. France et al. · Cancer Cell · 2004 · 643 citations · Full text

Signal Transduction, Signaling Pathway, Natural Sciences +3

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

Andrew L. Kung, Sonya Zabludoff, Dennis S. France et al. · Cancer Cell · 2004 · 474 citations · Full text

Transcriptional Coactivation, Transcriptional Regulation, Redox Regulator +9

ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity

Neru Munshi, Sébastien Jeay, Youzhi Li et al. · Molecular Cancer Therapeutics · 2010 · 319 citations

Antitumor Activity, Cell Death, Pharmacotherapy +18

Psammaplins from the Sponge <i>Pseudoceratina </i><i>p</i><i>urpurea:</i> Inhibition of Both Histone Deacetylase and DNA Methyltransferase

Ivette C. Piña, Jeffrey T. Gautschi, Gui-Yang-Sheng Wang et al. · The Journal of Organic Chemistry · 2003 · 307 citations

Epigenetic Change, Molecular Biology, Dna Methyltransferase +22

Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2

Steven J. Freedman, Zhenyu Sun, Andrew L. Kung et al. · Nature Structural & Molecular Biology · 2003 · 203 citations

Transcriptional Regulation, Signal Transduction, Biochemistry +9