Sébastien Jeay

ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity

Neru Munshi, Sébastien Jeay, Youzhi Li et al. · Molecular Cancer Therapeutics · 2010 · 320 citations

Medicine, Oncology, Pharmacology +17

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

Elizabeth C. Townsend, Mark A. Murakami, Alexandra Christodoulou et al. · Cancer Cell · 2016 · 304 citations · Full text

Medicine, Biomedical Sciences, Drug Discovery +6

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Philipp Holzer, Keiichi Masuya, Pascal Furet et al. · Journal of Medicinal Chemistry · 2015 · 206 citations · Full text

Medicine, Oncology, Pharmacology +15

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

Clemens Krepler, Katrin Sproesser, Patricia Brafford et al. · Cell Reports · 2017 · 159 citations · Full text

Medicine, Cancer Biology, Oncology +17

The Propeptide Domain of Lysyl Oxidase Induces Phenotypic Reversion of Ras-transformed Cells

Amitha H. Palamakumbura, Sébastien Jeay, Ying Guo et al. · Journal of Biological Chemistry · 2004 · 131 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14