Philipp Holzer

Click chemistry in materials synthesis. 1. Adhesive polymers from copper‐catalyzed azide‐alkyne cycloaddition

David Díaz Díaz, Sreenivas Punna, Philipp Holzer et al. · Journal of Polymer Science Part A Polymer Chemistry · 2004 · 419 citations

Copper Compounds, Engineering, Click Chemistry +16

Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors

Philipp Holzer, Keiichi Masuya, Pascal Furet et al. · Journal of Medicinal Chemistry · 2015 · 202 citations · Full text

Dihydroisoquinolinone Derivative, Drug Target, Molecular Biology +18

The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis

Georg Martiny‐Baron, Philipp Holzer, Éric Billy et al. · Angiogenesis · 2010 · 124 citations · Full text

A Supramolecular Enzyme Mimic That Catalyzes the 15,15′ Double Bond Scission of ,-Carotene

Richard R. French, Philipp Holzer, Michele Leuenberger et al. · Angewandte Chemie International Edition · 2000 · 103 citations · Full text

Bioorganic Chemistry, Engineering, Molecular Biology +18

A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097

Sébastien Jeay, Swann Gaulis, Stéphane Ferretti et al. · eLife · 2015 · 87 citations · Full text