Georg Martiny‐Baron

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

Georg Martiny‐Baron, Marcelo G. Kazanietz, Harald Mischak et al. · Journal of Biological Chemistry · 1993 · 1.6K citations · Full text

Medicine, Molecular Biology, Pharmacology +12

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

J M Wood, Guido Bold, Elisabeth Buchdunger et al. · PubMed · 2000 · 847 citations

Medicine, Oncology, Pharmacology +16

Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.

Harald Mischak, J.A. Goodnight, Walter Kölch et al. · Journal of Biological Chemistry · 1993 · 545 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Carlos Garcı́a-Echeverrı́a, Mark Pearson, Andreas Marti et al. · Cancer Cell · 2004 · 538 citations · Full text

Medicine, Medicinal Chemistry, Oncology +9

Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor

Sauveur-Michel Maira, Sabina Pecchi, Alan Huang et al. · Molecular Cancer Therapeutics · 2011 · 529 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13