Sabina Pecchi

Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor

Sauveur-Michel Maira, Sabina Pecchi, Alan Huang et al. · Molecular Cancer Therapeutics · 2011 · 524 citations

Pharmacotherapy, Different Selectivity Profile, Chemical Biology +26

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Matthew T. Burger, Sabina Pecchi, Allan S. Wagman et al. · ACS Medicinal Chemistry Letters · 2011 · 248 citations · Full text

2,4-Bismorpholino 6-Heterocyclic Pyrimidines, Pi3 Kinase Inhibitor, Orally Bioavailable Class +18

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Paul A. Renhowe, Sabina Pecchi, Cynthia M. Shafer et al. · Journal of Medicinal Chemistry · 2008 · 134 citations · Full text

Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor

Alexei S. Karpov, Payman Amiri, Cornelia Bellamacina et al. · ACS Medicinal Chemistry Letters · 2015 · 102 citations · Full text

Drug Target, Molecular Biology, Pharmacotherapy +16

4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors

Zhi‐Jie Ni, Paul A. Barsanti, Nathan Brammeier et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 70 citations · Full text

Medicinal Chemistry, Potent Chk-1 Inhibitors, Medicine +6