Concepedia

Cynthia M. Shafer

CM

Statistics

Publications

31

Citations

1.2K

H-Index

18

Active since

1996

Affiliations

Novartis (Switzerland)(Current)

University of California, Davis

Novartis (United States)

Gilead Sciences (United States)

Cynthia M. Shafer is an author at Novartis (Switzerland) specializing in pharmacology, medicinal chemistry, and drug discovery.

Top concepts

Publications per year

1996–2019

31

Publications

31

Design, Structure−Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors

Paul A. Renhowe, Sabina Pecchi, Cynthia M. Shafer et al. · Journal of Medicinal Chemistry · 2008 · 134 citations · Full text

Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor

Young Shin Cho, Julian Levell, Gang Liu et al. · ACS Medicinal Chemistry Letters · 2017 · 113 citations · Full text

Mechanism for Acivicin Inactivation of Triad Glutamine Amidotransferases

Sridar V. Chittur, Thomas J. Klem, Cynthia M. Shafer et al. · Biochemistry · 2001 · 90 citations

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Rama Jain, Michelle Mathur, Jiong Lan et al. · Journal of Medicinal Chemistry · 2015 · 82 citations · Full text

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Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors

Savithri Ramurthy, Sharadha Subramanian, Mina Aikawa et al. · Journal of Medicinal Chemistry · 2008 · 76 citations · Full text

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