Young Shin Cho

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, E. Robert McDonald, Michael R. Schlabach et al. · Science · 2016 · 580 citations

Medicine, Cancer Biology, Oncology +16

Preparation and Evaluation of Unimolecular Pentavalent and Hexavalent Antigenic Constructs Targeting Prostate and Breast Cancer:  A Synthetic Route to Anticancer Vaccine Candidates

Govind Ragupathi, Fusataka Koide, Philip O. Livingston et al. · Journal of the American Chemical Society · 2006 · 150 citations

Medicine, Immunology, Oncology +17

Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor

Young Shin Cho, Julian Levell, Gang Liu et al. · ACS Medicinal Chemistry Letters · 2017 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Discovery of (<i>E</i>)<i>-</i>9,10-Dehydroepothilones through Chemical Synthesis:  On the Emergence of 26-Trifluoro-(<i>E</i>)-9,10-dehydro-12,13-desoxyepothilone B as a Promising Anticancer Drug Candidate

Alexey Rivkin, Fumihiko Yoshimura, Ana E. Gabarda et al. · Journal of the American Chemical Society · 2004 · 99 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Design and Total Synthesis of a Superior Family of Epothilone Analogues, which Eliminate Xenograft Tumors to a Nonrelapsable State

Ting‐Chao Chou, Huajin Dong, Alexey Rivkin et al. · Angewandte Chemie International Edition · 2003 · 67 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9