Ana E. Gabarda

Discovery of (<i>E</i>)<i>-</i>9,10-Dehydroepothilones through Chemical Synthesis:  On the Emergence of 26-Trifluoro-(<i>E</i>)-9,10-dehydro-12,13-desoxyepothilone B as a Promising Anticancer Drug Candidate

Alexey Rivkin, Fumihiko Yoshimura, Ana E. Gabarda et al. · Journal of the American Chemical Society · 2004 · 96 citations

Compound 7, Medicinal Chemistry, Derivative (Chemistry) +15

Complex Target-Oriented Total Synthesis in the Drug Discovery Process:  The Discovery of a Highly Promising Family of Second Generation Epothilones

Alexey Rivkin, Fumihiko Yoshimura, Ana E. Gabarda et al. · Journal of the American Chemical Society · 2003 · 91 citations

Combinatorial Chemistry, Medicinal Chemistry, Second Generation Epothilones +15

Total Synthesis of Reblastatin

Iwona Wrona, Ana E. Gabarda, Gwilherm Evano et al. · Journal of the American Chemical Society · 2005 · 73 citations

19-Membered Macrolactam, Biochemistry, Medicine +11

Design and Total Synthesis of a Superior Family of Epothilone Analogues, which Eliminate Xenograft Tumors to a Nonrelapsable State

Ting‐Chao Chou, Huajin Dong, Alexey Rivkin et al. · Angewandte Chemie International Edition · 2003 · 66 citations

Pharmacotherapy, Promising Profiles, Practical Total Synthesis +19

Discovery of a 5<i>H</i>-Benzo[4,5]cyclohepta[1,2-<i>b</i>]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer

Jason D. Katz, James P. Jewell, David Guérin et al. · Journal of Medicinal Chemistry · 2011 · 60 citations · Full text

Tumor Biology, Aberrant C-met Signaling, Drug Target +14