Michelle Mathur

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Rama Jain, Michelle Mathur, Jiong Lan et al. · Journal of Medicinal Chemistry · 2015 · 82 citations · Full text

Drug Target, Chemoprevention Strategy, Rsk Kinase Family +17

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han et al. · Journal of Medicinal Chemistry · 2015 · 72 citations · Full text

Hematological Malignancy, Moloney Murine Leukemia, Medicinal Chemistry +14

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Matthew T. Burger, Wooseok Han, Jiong Lan et al. · ACS Medicinal Chemistry Letters · 2013 · 52 citations · Full text

Drug Target, Pan-pim Kinase Inhibitors, Chemical Biology +19

Structure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors

Paul A. Barsanti, Yue Pan, Yipin Lu et al. · ACS Medicinal Chemistry Letters · 2014 · 27 citations · Full text

Pharmaceutical Science, Drug Target, Indole Moiety +19

2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors

Abran Costales, Michelle Mathur, Savithri Ramurthy et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 26 citations · Full text

2-Amino-7-substituted Benzoxazole Analogs, Medicinal Chemistry, Medicine +5