Savithri Ramurthy

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Rama Jain, Michelle Mathur, Jiong Lan et al. · Journal of Medicinal Chemistry · 2015 · 82 citations · Full text

Drug Target, Chemoprevention Strategy, Rsk Kinase Family +17

Design and Synthesis of Orally Bioavailable Benzimidazoles as Raf Kinase Inhibitors

Savithri Ramurthy, Sharadha Subramanian, Mina Aikawa et al. · Journal of Medicinal Chemistry · 2008 · 76 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Science +13

4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors

Zhi‐Jie Ni, Paul A. Barsanti, Nathan Brammeier et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 70 citations · Full text

Medicinal Chemistry, Potent Chk-1 Inhibitors, Medicine +6

Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma

Teresa E. Williams, Sharadha Subramanian, Joelle Verhagen et al. · ACS Medicinal Chemistry Letters · 2015 · 53 citations · Full text

Medicinal Chemistry, Drug Target, Oncology +15

Design and Discovery of <i>N</i>-(2-Methyl-5′-morpholino-6′-((tetrahydro-2<i>H</i>-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

Gisele Nishiguchi, Alice Rico, Huw R. Tanner et al. · Journal of Medicinal Chemistry · 2017 · 44 citations · Full text

Drug Target, Kras Mutant Tumors, Kinase Inhibitors +17