Teresa E. Williams

Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the Treatment of Metastatic Melanoma

Teresa E. Williams, Sharadha Subramanian, Joelle Verhagen et al. · ACS Medicinal Chemistry Letters · 2015 · 53 citations · Full text

Medicinal Chemistry, Drug Target, Oncology +15

Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model

Wooseok Han, Daniel L. Menezes, Yongjin Xu et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 27 citations · Full text

Design, Structure–Activity Relationship, and in Vivo Characterization of the Development Candidate NVP-HSP990

Christopher M. McBride, Barry H. Levine, Yi Xia et al. · Journal of Medicinal Chemistry · 2014 · 27 citations · Full text

Structure–activity Relationship, Pharmaceutical Science, Commercial Hit +16

Design and Synthesis of Orally Bioavailable Benzimidazole Reverse Amides as Pan RAF Kinase Inhibitors

Sharadha Subramanian, Abran Costales, Teresa E. Williams et al. · ACS Medicinal Chemistry Letters · 2014 · 13 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +11