Jiong Lan

Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers

Pablo D. García, John L. Langowski, Yingyun Wang et al. · Clinical Cancer Research · 2014 · 111 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Rama Jain, Michelle Mathur, Jiong Lan et al. · Journal of Medicinal Chemistry · 2015 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

Ida Aronchik, B.A. Appleton, Stephen E. Basham et al. · Molecular Cancer Research · 2014 · 78 citations

Medicine, Oncology, Pharmacology +10

Identification of <i>N</i>-(4-((1<i>R</i>,3<i>S</i>,5<i>S</i>)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies

Matthew T. Burger, Gisele Nishiguchi, Wooseok Han et al. · Journal of Medicinal Chemistry · 2015 · 76 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Matthew T. Burger, Wooseok Han, Jiong Lan et al. · ACS Medicinal Chemistry Letters · 2013 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13