B.A. Appleton - Concepedia

Concepedia

Author

B.A. Appleton

Novartis (Switzerland)ORCID

Also Known As

Appleton, Brent A., B. Appleton, B.A. Appleton, Brent A Appleton, Brent A. Appleton, Brent Appleton

91

Publications

3.1K

Citations

26

H-Index

55

Concepts

All Affiliations

Novartis (Switzerland)Harvard University Novartis (United States)University of Toronto University of Padua

BA

About

B.A. Appleton is an author at Novartis (Switzerland) specializing in medicine, natural sciences, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	18	20	2.1K
2	Natural Sciences	13	13	1.5K
3	Biochemistry	7	7	507
4	Biomolecular Engineering	2	2	135
5	Health Sciences	1	1	133

B.A. Appleton

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30

Publications

3.1K

Citations

26

H-Index

	Year	Citations
A Specificity Map for the PDZ Domain Family Raffi Tonikian, Yingnan Zhang, Stephen L. Sazinsky, PLoS Biology Specificity ProfilingMolecular BiologyTopological PropertySpecificity MapBinding Site	2008	469
Variants of the Antibody Herceptin That Interact with HER2 and VEGF at the Antigen Binding Site Jenny Boström, Shang‐Fan Yu, David Kan, Science	2009	362
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding B.A. Appleton, Ping Wu, Janice Maloney, The EMBO Journal Protein FunctionSignal TransductionNatural SciencesReceptor Tyrosine KinaseNeuropilin/antibody Complexes	2007	207
Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors—Insight into Heterotrimeric IL-1 Signaling Complexes Andreas Lingel, M. Niebuhr, Borlan Pan, Structure InflammationCytokineSignal TransductionImmunologyImmune Regulation	2009	205
Comprehensive Analysis of the Factors Contributing to the Stability and Solubility of Autonomous Human VH Domains Pierre A. Barthelemy, Helga Raab, B.A. Appleton, Journal of Biological Chemistry	2007	174
Inhibition of Wnt signaling by Dishevelled PDZ peptides Yingnan Zhang, B.A. Appleton, Christian Wiesmann, Nature Chemical Biology Signal TransductionSignaling PathwayMedicineReceptor Tyrosine KinaseDishevelled Pdz Peptides	2009	160
A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients Ralph Tiedt, Elisa Degenkolbe, Pascal Furet, Cancer Research Mixed-phenotype Acute LeukemiaCancer PatientsTumor BiologyDrug ResistanceHematological Malignancy	2011	133
GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis Jonathan M. Goodwin, Ward G. Walkup, Kirsty M. Hooper, Science Advances	2021	121
The Crystal Structure of Murine Coronin-1: A Regulator of Actin Cytoskeletal Dynamics in Lymphocytes B.A. Appleton, Ping Wu, Christian Wiesmann Structure Crystal StructureMedicineNatural SciencesActin Cytoskeletal DynamicsMolecular Biology	2006	119
Convergent and Divergent Ligand Specificity among PDZ Domains of the LAP and Zonula Occludens (ZO) Families Yingnan Zhang, Sherry Yeh, B.A. Appleton, Journal of Biological Chemistry	2006	103

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