Helga Raab

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Jagath R. Junutula, Helga Raab, Suzanna Clark et al. · Nature Biotechnology · 2008 · 1.3K citations

Medicinal Chemistry, Immunocytochemical Technique, Drug Targeting +10

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben‐Quan Shen, Keyang Xu, Luna Liu et al. · Nature Biotechnology · 2012 · 977 citations

Immunoengineering, Immunology, Bioconjugation +8

Molecular cloning and expression of a receptor for human tumor necrosis factor

Thomas J. Schall, Martyn Lewis, Kerry J. Koller et al. · Cell · 1990 · 966 citations · Full text

Inflammation, Cytokine, Disease Mechanism +8

Identification of Heregulin, a Specific Activator of p185 ^erbB2

William E. Holmes, Mark X. Sliwkowski, Robert W. Akita et al. · Science · 1992 · 958 citations

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

Sophie M. Lehar, Thomas H. Pillow, Min Xu et al. · Nature · 2015 · 815 citations

Antimicrobial Drug Discovery, Antimicrobial Susceptibility, Antibiotics +7