Robert W. Akita

Identification of Heregulin, a Specific Activator of p185 ^erbB2

William E. Holmes, Mark X. Sliwkowski, Robert W. Akita et al. · Science · 1992 · 958 citations

Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

Teemu T. Junttila, Robert W. Akita, Kathryn L. Parsons et al. · Cancer Cell · 2009 · 822 citations · Full text

Molecular Pharmacology, Signaling Pathway, Medicine +10

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin.

Mark X. Sliwkowski, Gabriele Schaefer, Robert W. Akita et al. · Journal of Biological Chemistry · 1994 · 643 citations · Full text

Breast Oncology, High Affinity Receptor, Immunology +20

Spatial control of EGF receptor activation by reversible dimerization on living cells

Inhee Chung, Robert W. Akita, Richard Vandlen et al. · Nature · 2010 · 536 citations

Signal Transduction, Developmental Biology, Tumor Microenvironment +10

Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease.

Michael F. Press, Malcolm C. Pike, V R Chazin et al. · PubMed · 1993 · 434 citations

Breast Oncology, Pathology, Breast Cancer Specimens +16