Stephen L. Sazinsky - Concepedia

Concepedia

Author

Stephen L. Sazinsky

Massachusetts Institute of Technology

Also Known As

Stephen L Sazinsky, Stephen L. Sazinsky, Stephen Sazinsky

20

Publications

2.1K

Citations

11

H-Index

46

Concepts

All Affiliations

Massachusetts Institute of Technology Rockefeller University University of Toronto

SL

About

Stephen L. Sazinsky is an author at Massachusetts Institute of Technology specializing in medicine, engineering, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	1K
2	Engineering	4	4	1.2K
3	Natural Sciences	3	3	758
4	Allergy	1	1	40
5	Biochemistry	1	1	97

Stephen L. Sazinsky

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11

Publications

2.1K

Citations

11

H-Index

	Year	Citations
Isolating and engineering human antibodies using yeast surface display Ginger Chao, Wai Leung Lau, Benjamin J. Hackel, Nature Protocols EngineeringBiotechnologySynthetic BiologyProtein EngineeringAntibody Engineering	2006	937
A Specificity Map for the PDZ Domain Family Raffi Tonikian, Yingnan Zhang, Stephen L. Sazinsky, PLoS Biology Specificity ProfilingMolecular BiologyTopological PropertySpecificity MapBinding Site	2008	469
Directed evolution of a secretory leader for the improved expression of heterologous proteins and full‐length antibodies in <i>Saccharomyces cerevisiae</i> James A. Rakestraw, Stephen L. Sazinsky, Andrea Piatesi, Biotechnology and Bioengineering Protein SecretionMutant AlphaMolecular BiologyMolecular GeneticsProtein Expression	2009	192
Aglycosylated immunoglobulin G<sub>1</sub>variants productively engage activating Fc receptors Stephen L. Sazinsky, René G. Ott, Nathaniel W. Silver, Proceedings of the National Academy of Sciences EngineeringImmunologyGlycobiologyImmunodominanceFc Gammars	2008	175
Stably folded de novo proteins from a designed combinatorial library Yinan Wei, Tun Liu, Stephen L. Sazinsky, Protein Science	2003	98
Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3 Steven Runyon, Yingnan Zhang, B.A. Appleton, Protein Science Serine Protease DomainProtein AssemblyMolecular BiologyFunctional AnalysisHuman Htra1	2007	97
Rapid Evolution of Functional Complexity in a Domain Family Andreas Ernst, Stephen L. Sazinsky, Shirley Hui, Science Signaling EngineeringGeneticsMolecular BiologyComputational ComplexityDomain Mutation	2009	53
Comprehensive Experimental and Computational Analysis of Binding Energy Hot Spots at the NF-κB Essential Modulator/IKKβ Protein–Protein Interface Mary S. Golden, Shaun Cote, Marianna Sayeg, Journal of the American Chemical Society	2013	47
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models Amanda Hanson, Kutlu G. Elpek, Ellen Duong, PLoS ONE T-regulatory CellImmunologyImmunoeditingImmunologic MechanismAnti-tumor Immunity	2020	40
Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs Tiffany F. Chen, Stephen L. Sazinsky, Damian J. Houde, Journal of Molecular Biology EngineeringAutoimmune DiseaseGlycobiologyImmunologyGenetic Engineering	2017	17

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