Concepedia

Christine Hiu-Tung Chen

CH

Statistics

Publications

6

Citations

1.6K

H-Index

6

Active since

2012

Affiliations

Novartis (United States)(Current)

Christine Hiu-Tung Chen is an author at Novartis (United States) specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

2012–2020

6

Publications

6

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

, , +16

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen et al. · Journal of Medicinal Chemistry · 2016 · 291 citations · Full text

, , +17

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 222 citations · Full text

, , +17

Identification of NVP-TNKS656: The Use of Structure–Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor

Michael D. Shultz, Atwood K. Cheung, C.A. Kirby et al. · Journal of Medicinal Chemistry · 2013 · 123 citations · Full text

, , +17

Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors

Young Shin Cho, Hayley C. Angove, Christopher T. Brain et al. · ACS Medicinal Chemistry Letters · 2012 · 46 citations · Full text

, , +17

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