Christopher T. Brain

Novel procedure for the synthesis of 1,3,4-oxadiazoles from 1,2-diacylhydrazines using polymer-supported Burgess reagent under microwave conditions

Christopher T. Brain, Jane M. Paul, Yvonne Loong et al. · Tetrahedron Letters · 1999 · 179 citations

Polymer-supported Burgess Reagent, Novel Procedure, Organic Chemistry +5

An intramolecular palladium-catalysed aryl amination reaction to produce benzimidazoles

Christopher T. Brain, Shirley A. Brunton · Tetrahedron Letters · 2002 · 165 citations

Cross-coupling Reaction, Engineering, Organic Chemistry +3

An Improved Procedure for the Synthesis of Benzimidazoles, Using Palladium-Catalyzed Aryl-Amination Chemistry

Christopher T. Brain, James T. Steer · The Journal of Organic Chemistry · 2003 · 145 citations

Cross-coupling Reaction, Engineering, Excellent Yield +10

Antiproliferative Effects of CDK4/6 Inhibition in <i>CDK4</i> -Amplified Human Liposarcoma <i>In Vitro</i> and <i>In Vivo</i>

Yi-Xiang Zhang, Ewa Sicińska, Jeffrey T. Czaplinski et al. · Molecular Cancer Therapeutics · 2014 · 111 citations

Abstract PR02: LEE011: An orally bioavailable, selective small molecule inhibitor of CDK4/6– Reactivating Rb in cancer.

Sunkyu Kim, Alice Loo, Rajiv Chopra et al. · Molecular Cancer Therapeutics · 2013 · 104 citations

Abstract Pr02, Alan Huang, Cancer Biology +16