Concepedia

Timothy M. Ramsey

TM

Statistics

Publications

25

Citations

2.8K

H-Index

19

Active since

1992

Affiliations

Scripps Research Institute(Current)

Novartis (Switzerland)

University of Oklahoma

Dana-Farber Cancer Institute

Massachusetts Institute of Technology

Timothy M. Ramsey is an author at Scripps Research Institute specializing in chemistry, medicinal chemistry, and pharmacy.

Publications per year

1992–2024

25

Publications

25

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan et al. · Nature · 2016 · 929 citations

, , +16

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Ying-Nan P. Chen, Sushil Sharma, Timothy M. Ramsey et al. · Proceedings of the National Academy of Sciences · 1999 · 319 citations

, , +17

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Jorge Fortanet, Christine Hiu-Tung Chen, Ying-Nan P. Chen et al. · Journal of Medicinal Chemistry · 2016 · 291 citations · Full text

, , +17

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Matthew J. LaMarche, Michael Acker, Andreea Argintaru et al. · Journal of Medicinal Chemistry · 2020 · 222 citations · Full text

, , +17

Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 5:  Linkage of Fragments C<sub>1</sub><sub>-</sub><sub>6</sub> and C<sub>7</sub><sub>-</sub><sub>24</sub> and Finale

Stuart J. Mickel, Daniel Niederer, Robert Daeffler et al. · Organic Process Research & Development · 2003 · 142 citations

, , +13

1–5 of 25