An engineered Cas12i nuclease that is an efficient genome editing tool in animals and plants

Highly accurate protein structure prediction with AlphaFold

John Jumper, Alexander Pritzel, Tim Green et al. · Nature · 2021 · 42K citations · Full text

WebLogo: A Sequence Logo Generator: Figure 1

Gavin E. Crooks, Gary C. Hon, John‐Marc Chandonia et al. · Genome Research · 2004 · 12.7K citations · Full text

Interactive Visualization, Engineering, Sequence Logos +13

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Cell · 2015 · 4.7K citations · Full text

Rna Processing, Off-target Effect, Medicine +11

Efficient transformation of rice (<i>Oryza sativa</i> L.) mediated by <i>Agrobacterium</i> and sequence analysis of the boundaries of the T‐DNA

Yukoh Hiei, Shozo Ohta, Toshihiko Komari et al. · The Plant Journal · 1994 · 3.5K citations · Full text

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen et al. · Nature Biotechnology · 2014 · 2.2K citations · Full text

Off-target Effect, Genetics, Gene Editing +7