Food & Function · 2021 · 57 citations · 37 references
MedicineEndocrinologyPharmacologyCarbohydrate BiochemistryCell SignalingDiabetologyDiabetes MellitusInsulin ResistancePlant Cell Wall PolysaccharidesPolysaccharide FunctionPolysaccharide PropertiesPolysaccharide StructureAntidiabetic ActivityAntidiabetic InteractionsDiabetes Mellitus PathophysiologyInsulin Secretion EnhancementPolysaccharide CharacterizationPolysaccharide Natural ProductsStructural Roles Of PolysaccharidesType 2 Diabetes Mellitus Pathogenesis
. Furthermore, RT-qPCR analysis results clarified that UPP administration distinctly activated the IRS/PI3K/AKT signaling pathway, restrained PEPCK, G-6-Pase and Egr-1 genes, and affected the relative expression of HMGCR and LDLR genes. This study demonstrates that UPP could be applied as an adjuvant agent for the management of T2DM.
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