Artocarpus lakoocha Roxb. and Artocarpus heterophyllus Lam. Flowers: New Sources of Bioactive Compounds

Abstract

<i>Artocarpus heterophyllus</i> Lam. (<i>AH</i>) and <i>Artocarpus lakoocha</i> Roxb. (<i>AL</i>) are two endemic plants that grow on the Asian continent. To date, their applications have been aimed at using their fruit as a food source or for some of their therapeutic virtues. In this study, attention was given to the flowers of <i>AH</i> and <i>AL</i>. Initially, the cytotoxicity of the phytoextracts was assessed, and the content of minerals, phenols, and flavonoids was determined. Furthermore, some antioxidant components were identified by HPLC. Furthermore, the ability of <i>AH</i> and <i>AL</i> extracts to modulate the gene expression of some targets involved in the antioxidant response was studied. The results obtained highlighted the nutritional and antioxidant value of the <i>AH</i> and <i>AL</i> flower extracts. This study will contribute to enhancing the use of <i>AH</i> and <i>AL</i> flowers as potential supplements in human nutrition.