Nature · 2020 · 310 citations · 23 references
Life SciencesMolecular BiologyOncologyChromatin BiologyChromatin StructureDna RepairChromatinDna DamageDna Damage SignalingDna Double-strand Break RepairDna Strand BreaksHistone ModificationsChromatin During Dna RepairChromatin Remodeling After Dna DamageChromatin Remodeling During RepairChromatin StabilityDna Repair Mechanisms
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text
Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 2K citations · Full text
Medicine, Cancer Biology, Oncology +14
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
Andrew J. Pierce, Roger D. Johnson, L.H. Thompson et al. · Genes & Development · 1999 · 1.4K citations · Full text