Gurpreet S. Kapoor

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

Life Sciences, Genetics, Molecular Biology +14

Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

Christopher A. Benetatos, Yasuhiro Mitsuuchi, Jennifer M. Burns et al. · Molecular Cancer Therapeutics · 2014 · 175 citations

Life Sciences, Oncology, Pharmacology +17

One-way Cross-talk between p38MAPK and p42/44MAPK

Rajesh P. Singh, Punita Dhawan, Carmen Golden et al. · Journal of Biological Chemistry · 1999 · 152 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

Stephen M. Condon, Yasuhiro Mitsuuchi, Yijun Deng et al. · Journal of Medicinal Chemistry · 2014 · 151 citations

Medicine, Oncology, Pharmacology +13

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells

Ángel Ayuso‐Sacido, Jennifer Moliterno, Sebila Kratovac et al. · Journal of Neuro-Oncology · 2009 · 123 citations

Life Sciences, Cell Biology, Developmental Biology +13