Patrick S. Ward

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text

Medicine, Genetics, Molecular Genetics +10

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Medicine, Genetics, Hematology +17

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +14

The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

Patrick S. Ward, Jay Patel, David R. Wise et al. · Cancer Cell · 2010 · 2K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

Sneha Rath, Rohit Sharma, Rahul Gupta et al. · Nucleic Acids Research · 2020 · 2K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16