The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate - Concepedia

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The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate

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23

References

2010

Year

Patrick S. Ward, Jay Patel, David R. Wise, Omar Abdel‐Wahab, Bryson D. Bennett, Hilary A. Coller, Justin R. Cross, Valeria R. Fantin, Cyrus V. Hedvat, Alexander E. Perl,

Somatic VariantBiochemistryMedicineGeneticsInherited Metabolic DiseaseMixed-phenotype Acute LeukemiaLeukemia-associated Idh1Common FeatureMolecular GeneticsCancer GeneticsIdh2 MutationsCancer MetabolismTumor Biology

References

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