Concepedia

Metabolic Reprogramming

Metabolic Reprogramming is a hallmark of cancer cells characterized by the adaptive alteration of cellular metabolic pathways to support tumor growth, survival, and proliferation within the dynamic constraints of the tumor microenvironment.

17.3K

Publications

1.3M

Citations

102.5K

Authors

7.8K

Institutions

Publications per year

2017–2026

9.9K

Parents

Children

Publications

17.3K

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

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Comprehensive molecular characterization of clear cell renal cell carcinoma

Nature · 2013 · 3.5K citations · Full text

, , +17

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih‐Hao Chang, Jing Qiu, David O’Sullivan et al. · Cell · 2015 · 3.2K citations · Full text

, , +16

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Cantó, Zachary Gerhart‐Hines, Jérôme N. Feige et al. · Nature · 2009 · 3.2K citations · Full text

, , +15

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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1–5 of 17.3K

Authors

102.5K

  1. RJ
    Ralph J. DeBerardinis

    The University of Texas Southwestern Medical Center, United States

    73 publications · 17.6K citations

    56

    h-index

  2. JM
    John M. Asara

    Beth Israel Deaconess Medical Center, United States

    71 publications · 19.9K citations

    51

    h-index

  3. FS
    Federica Sotgia

    Thomas Jefferson University, United States

    54 publications · 8.9K citations

    46

    h-index

  4. MP
    Michael P. Lisanti

    Albert Einstein College of Medicine, United States

    58 publications · 9.2K citations

    46

    h-index

  5. MG
    Matthew G. Vander Heiden

    Massachusetts Institute of Technology, United States

    56 publications · 16.1K citations

    46

    h-index

1–5 of 102.5K

Institutions

7.8K

  1. Harvard University

    Cambridge, United States

    149 h-index

    2.4K publications

    503.9K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    112 h-index

    853 publications

    277.3K citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    108 h-index

    2.3K publications

    426.7K citations

  4. Inserm

    Paris, France

    103 h-index

    2.4K publications

    216.8K citations

  5. The University of Texas Southwestern Medical Center

    Dallas, United States

    97 h-index

    1.3K publications

    251.3K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    96 h-index

    376 publications

    89.6K citations

  7. Sun Yat-sen University

    Guangzhou, China

    94 h-index

    2.5K publications

    210.6K citations

  8. University of Pennsylvania

    Philadelphia, United States

    91 h-index

    869 publications

    211.1K citations

1–8 of 7.8K

Venues

  1. Nature Communications

    411 publications · 48.4K citations

    126

    h-index

  2. Cancer Research

    404 publications · 46.7K citations

    123

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 294 publications · 49.9K citations

    122

    h-index

  4. Cell Metabolism

    159 publications · 40.6K citations

    113

    h-index

  5. Journal of Biological Chemistry

    JBC · 382 publications · 39.7K citations

    108

    h-index

1–5