David O’Sullivan

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih‐Hao Chang, Jing Qiu, David O’Sullivan et al. · Cell · 2015 · 3.1K citations · Full text

Tumor Biology, Oncology, Medicine +11

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.1K citations · Full text

Signal Transduction, Aerobic Glycolysis, Cell Signaling +8

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming

Michael D. Buck, David O’Sullivan, Ramon I. Klein Geltink et al. · Cell · 2016 · 1.4K citations · Full text

Mitochondrial Function, Mitochondrial Dynamic, Metabolic Programming +5

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Stanley Ching‐Cheng Huang, Bart Everts, Yulia Ivanova et al. · Nature Immunology · 2014 · 1.2K citations · Full text

Inflammation, Macrophage Biology, Cell Autophagy +11

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

David O’Sullivan, Gerritje J. W. van der Windt, Stanley Ching‐Cheng Huang et al. · Immunity · 2014 · 761 citations · Full text

Engineering, Metabolic Programming Necessary, Metabolic Engineering +10