Concepedia

Heather R. Christofk

HR

64

Publications

13.2K

Citations

43

H-Index

2004

Active since

Affiliations

University of California, Los Angeles(Current)

Broad Center

UCLA Jonsson Comprehensive Cancer Center

Harvard University

Beth Israel Deaconess Medical Center

Heather R. Christofk is an author at University of California, Los Angeles specializing in medicine, cell biology, and biochemistry.

ORCID

Top concepts

Publications per year

2004–2024

64

Publications

64

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

, , +9

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Heather R. Christofk, Matthew G. Vander Heiden, Ning Wu et al. · Nature · 2008 · 999 citations

, , +6

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou, Yimin Yu, William J. Israelsen et al. · Nature Chemical Biology · 2012 · 804 citations · Full text

Evidence for an alternative glycolytic pathway in rapidly proliferating cells

Matthew G. Vander Heiden, Jason W. Locasale, Kenneth D. Swanson et al. · Europe PMC (PubMed Central) · 2010 · 633 citations

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

R Chin, Xudong Fu, Melody Y. Pai et al. · Nature · 2014 · 598 citations · Full text

, , +13

Rows per page

1–5 of 64