R Chin

Target identification using drug affinity responsive target stability (DARTS)

Brett Lomenick, Rui Hao, Nao Jonai et al. · Proceedings of the National Academy of Sciences · 2009 · 1.1K citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +13

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

R Chin, Xudong Fu, Melody Y. Pai et al. · Nature · 2014 · 612 citations · Full text

Life Sciences, Biochemistry, Physiology +14

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

Xudong Fu, R Chin, Laurent Vergnes et al. · Cell Metabolism · 2015 · 241 citations · Full text

Life Sciences, Biochemistry, Cell Biology +9

Interaction of immunoactive monokines (interleukin 1 and tumor necrosis factor) in the bivalve mollusc Mytilus edulis.

Thomas K. Hughes, Eric M. Smith, R Chin et al. · Proceedings of the National Academy of Sciences · 1990 · 129 citations

Life Sciences, Immunology, Physiology +15

Optimized Mitochondrial Targeting of Proteins Encoded by Modified mRNAs Rescues Cells Harboring Mutations in mtATP6

R Chin, Tadas Panavas, Jeffrey M. Brown et al. · Cell Reports · 2018 · 51 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17