Laurent Vergnes

Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi Shimada, Timothy R. Crother, Justin N. Karlin et al. · Immunity · 2012 · 2.1K citations · Full text

Mitochondrial Function, Apoptosis, Molecular Biology +5

The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR

R Chin, Xudong Fu, Melody Y. Pai et al. · Nature · 2014 · 598 citations · Full text

Lifespan Extension, Metabolite α-Ketoglutarate Extends, Energy Metabolism +13

Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Yoko Kidani, Heidi Elsaesser, M. Benjamin Hock et al. · Nature Immunology · 2013 · 531 citations · Full text

Lipid Synthesis, Immune Cell Development, Metabolic Programming +12

Metabolic state of glioma stem cells and nontumorigenic cells

Erina Vlashi, Chann Lagadec, Laurent Vergnes et al. · Proceedings of the National Academy of Sciences · 2011 · 528 citations · Full text

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

Jin Zhang, Ivan Khvorostov, Jason Hong et al. · The EMBO Journal · 2011 · 502 citations

Induced Pluripotent Stem Cell, Energy Metabolism, Developmental Biology +9